Program Description
Are you interested in biological processes such as cell development, growth and heredity? Then take a seat at one of CMU’s lab benches, with a major in biochemistry. You’ll study the chemistry of living systems in pharmaceutical, diagnostic, agricultural and environmental products that are manufactured or used by biological molecules such as DNA and proteins. Biochemistry faculty at CMU prepare professionals who are able to excel in biotechnology, health professions, pharmaceutical industries and forensics, as well as in the traditional yet exciting roles of chemistry and biology.
Points of Pride
- Use your skills of discovery to make life better. CMU is a Carnegie-classified doctoral research institution. Its faculty and students – including undergrads – work elbow-to-elbow to change lives by researching cancer vaccines and better treatment for Huntington's, Parkinson's and Alzheimer's diseases.
- CMU’s $95 million Biosciences Building is the largest capital project ever in the university’s 120-plus year history. The four-story, 169,000-square-foot building, opening for classes in January 2017, will dramatically advance the university’s instructional learning and scientific research space.
Put Your Degree to Work
Biochemistry graduates have a variety of career options, including work as an agricultural chemist, biochemist, college or university professor, environmental chemist, high school teacher, materials scientist or toxicologist. Employment of biochemists is projected to grow 19 percent from 2012 to 2022, faster than the average for all occupations. More biochemists will be needed to develop biological products and processes that improve our lives.
U.S. Bureau of Labor Statistics sample data
| Job | Median Pay | Job Growth through 2022 |
|---|
| Chemist | $73,060 per year | 6% (5,400 more jobs) |
| Environmental scientist | $63,570 per year | 15% (13,200 more jobs) |
| Postsecondary teacher | $68,970 per year | 19% (236,400 more jobs) |
Program Overview
The course listings below are a representation of what this academic program requires. For a full review of this program in detail please see our official online academic bulletin AND consult with an academic advisor. This listing does not include the General Education courses required for all majors and may not include some program specific information, such as admissions, retention, and termination standards.
(Click on the course name or number for a complete course description.)
Biochemistry Major
Total: 71 semester hours
Note: A minor in Chemistry is not allowed with a Biochemistry major.
Core Courses II
(21 hours)
CHM 211QR
Quantitative Analysis
4
Analysis and interpretation of quantitative chemical information from volumetric, electrochemical, spectroscopic, and chromatographic techniques. This course may be offered in an online/hybrid format. Prerequisite: CHM 132 or 161. Recommended: MTH 107. Quantitative Reasoning.
CHM 345
Organic Chemistry I
3
Overview of common organic reactions. Reactions of alkanes, alkenes, alkynes, and alkyl halides, Ultraviolet/Visible, Infrared, and Nuclear Magnetic Resonance spectroscopy, mass spectrometry. Prerequisite: CHM 132 or 161.
CHM 346
Organic Chemistry II
3
Continuation of CHM 345. Overview of common organic reactions of aromatic compounds, alcohols, carbonyl compounds, and amines. Prerequisite: CHM 345.
CHM 349
Organic Chemistry Laboratory
2
Laboratory techniques in organic chemistry; methods of synthesis, separation, purification, structure determination - spectroscopic methods; utilization of electronic database (Scifinder) searching techniques. Prerequisite: CHM 345. Pre/Co-requisite: CHM 346.
CHM 521
Fundamentals of Biochemistry
3
Structure, function, and metabolism of proteins, carbohydrates, lipids, and nucleic acids. Prerequisites: CHM 346.
CHM 522
Intermediate Biochemistry
3
Continuation of CHM 521. Material covered will include in-depth exploration of metabolism of biomacromolecules and biochemical processes requiring their use. Prerequisites: CHM 521.
CHM 527
Biochemistry Laboratory
1
Isolation, characterization, and analysis of proteins, carbohydrates, lipids, vitamins, and nucleic acids using chromatographic, electrophoretic, and spectroscopic techniques. Prerequisite: CHM 211, CHM 349. Pre/Co-Requisite: CHM 425 or CHM 521.
CHM 528
Bioanalytical Techniques Laboratory
2
Laboratory analysis of biochemical materials using volumetric, electroanalytical, spectroscopic, and chromatographic techniques. Prerequisites: CHM 211 or graduate standing; Pre/Co-requisite: CHM 425 or 521.
Core Courses I
(5-8 hours)
Select one of the following options:
MR2A-BIOCHEM
Option A
(8 hours)
MR2B-BIOCHEM
Option B
(5 hours)
Core Courses III
(3 hours)
Select one of the following:
Laboratory experience emphasizing the theory and practice of techniques used in basic cell and molecular biology research and their applications in biotechnology. May be offered as Writing Intensive. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 211 with a grade of C- or better and a signed major in Biochemistry; or BIO 324 or 326; CHM 132.
BIO 524
Molecular Biology
3
Molecular nature of genes and recombinant DNA techniques, explored through the analysis of experimental data. Prerequisites: BIO 326, CHM 346; or graduate standing. Recommended: CHM 521, 522.
Core Courses IV
(3-6 hours)
Select one of the following options:
MR4A-BIOCHEM
Option A
(3 hours)
MR4B-BIOCHEM
Option B
(6 hours)
Core Course V
(3 hours)
CHM 491WI
Undergraduate Research
1-3
Culminating experience for chemistry/biochemistry majors: Research; capstone thesis. Development of critical thinking, laboratory skills, instrumentation competence, scientific reasoning and communication skills. Writing Intensive. Prerequisites: 8 credits of chemistry courses and permission of instructor.
Required Courses I
(20 hours)
BIO 111
Foundations of Evolution and Diversity
4
Basic principles of evolution and the application of these principles to the history and diversity of life. Satisfies University Program Group II laboratory requirement. (University Program Group II-A: Descriptive Sciences)
BIO 112
Foundations of Cell Biology
4
Structure and function of bacteria, archaea, and eukaryotic cells including biological molecules, bioenergetics, membrane transport, respiration, photosynthesis, cell communication, and cell division. Prerequisite: BIO 111 with a C- or better. Prerequisite/Co-requisite: CHM 131.
BIO 211
Foundations of Genetics
4
Foundations and applications of molecular and transmission genetics in a diversity of organisms. Prerequisite: BIO 112 with a C- or better. Prerequisite/Co-requisite: CHM 132.
Limits, continuity, interpretations of the derivative, differentiation of elementary functions, applications of derivatives, antiderivatives, Riemann sums, definite integrals, fundamental theorem of calculus. This course may be offered in an online or hybrid format. Recommended: MTH 107, 109; or MTH 130. (University Program Group II-B: Quantitative and Mathematical Sciences)
Techniques of integration, applications of definite integrals, improper integrals, elementary differential equations, infinite series, Taylor series, and polar coordinates. Prerequisite: MTH 132.
Required Courses II
(10 hours)
Select one of the following options:
OR8A-BIOCHEM
Option A
(10 hours)
OR8B-BIOCHEM
Option B
(10 hours)
Electives
(0-6 hours)
Sufficient 300 or greater CHM, BIO, or other courses, selected in consultation with program advisor, to met the required 71 hours.
Select from the following:
Suggestions for electives based on career goals are given below:
Pre-Medical, Pre-Veterinarian, and Pre-Dental: CHM 568, BIO 337, 392, 500, 580, 536, 537, 544.
Pre-Pharmacy (Note: Please check with websites of pharmacy schools you are applying since pre-requisites vary considerably): CHM 568, 337, 500.
Pre-Graduate School: CHM 333, BIO 545, 546, 575, 576.
BIO 320
Biology of Bacteria
3
Intermediate microbiology course focusing on bacterial cell structure and function, metabolism, genetics and phylogeny. Prerequisite: BIO 208.
Laboratory experience emphasizing the theory and practice of techniques used in basic cell and molecular biology research and their applications in biotechnology. May be offered as Writing Intensive. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 211 with a grade of C- or better and a signed major in Biochemistry; or BIO 324 or 326; CHM 132.
BIO 337
Comparative Vertebrate Anatomy
4
Anatomical survey illustrating major morphological characteristics within phylum Chordata emphasizing vertebrates. Ontogenetic and evolutionary trends are developed within the framework of functional morphology and adaptation. Prerequisites: BIO 218.
BIO 392
Mammalian Physiology
4
The functioning of the mammalian body and its component parts, with an emphasis on human systems. Prerequisites: A grade of C- or better in BIO 208 or 211; CHM 132 or 342.
BIO 397
Special Topics in Biology
1-6
Topics of special interest that are not normally included in existing courses. Prerequisites: Course prerequisites will be announced in the Course Search and Registration.
BIO 497
Special Topics in Biology
1-9
Topics of special interest that are not normally included in existing courses. Specific topics and instructor's prerequisites will be announced in Course Search and Registration. Repeatable up to 9 credits when content does not duplicate previous special topics.
BIO 500
Biological Statistics
3
An introduction to biological statistics; emphasis on concepts of descriptive statistics and central tendency, inferential statistics, one-way ANOVA and correlation/linear regression. Prerequisites: Graduate standing or twelve (12) hours of biology. Recommended MTH 130.
Mechanisms of descent with modification are discussed in a framework of microevolution, speciation, and macroevolution. Prerequisites: BIO 326 or graduate standing.
BIO 524
Molecular Biology
3
Molecular nature of genes and recombinant DNA techniques, explored through the analysis of experimental data. Prerequisites: BIO 326, CHM 346; or graduate standing. Recommended: CHM 521, 522.
Hormones, their synthesis, secretion, and their mode of action. Prerequisites: BIO 392 or graduate standing.
A study of the principle cells and tissues of humans. Prerequisites: BIO 218 and 392; or graduate standing.
A description of the biological and biochemical mechanisms of the immune response. Emphasis will be placed on adaptive immunity activation, immunobiology, and immune system dysfunction. Prerequisites: BIO 324, 326, 392; CHM 342 or 346; or graduate standing. Recommended: CHM 425 or 521.
Basic principles of viral structure and replication. Provides a detailed survey of viruses, including emergent viral pathogens. Explores viral evolution, anti-viral drugs and vaccines. Prerequisites: BIO 324, 326 or Graduate Status in the Biology Department.
BIO 544
Developmental Biology
4
Patterns and cellular/molecular mechanisms of embryonic development, emphasizing animals. Prerequisites: BIO 212, 213 with a grade of C- or better; or BIO 324, 326; CHM 132 or 161.
BIO 545
Molecular Genetics
3
Genetic approach to fundamental biological problems. Covers genetic techniques and modern molecular methods, including recombinant DNA technology and functional genomics in model systems and humans. Prerequisites: BIO 324, 326; CHM 345. Recommended: CHM 346.
BIO 546
Molecular Genetics Laboratory
1
Laboratory course, to accompany BIO 545, explores genetic techniques and modern molecular methods, including recombinant DNA technology and functional genomics in model systems. Pre/Co-requisites: BIO 545.
BIO 570
Cellular Dynamics
3
A course that explores advanced topics in cell biology focusing on landmark discoveries and experimental techniques using the primary literature. Prerequisites: BIO 324, 326; or Biology graduate status.
BIO 571
Cellular Dynamics Laboratory
1
An advanced laboratory course that explores experimental techniques in cell biology research. This is a laboratory course that accompanies BIO 570. Prerequisites: BIO 324, 326; or Biology graduate status. Co- requisite: BIO 570.
BIO 575
Applied Bioinformatics
4
Application of bioinformatics techniques. Topics include: gene finding, pairwise and multiple sequence alignments of DNA and protein sequences, and the use of GenBank and BLAST. Prerequisite: BIO 326 or graduate standing.
BIO 576
Animal Cell Culture
4
Practical aspects of animal cell culture, involving media preparation, aseptic manipulation of cell culture, cell maintenance, and cell storage. Recommended: BIO 392.
BIO 580
Medical Microbiology
4
Focuses on relationships between humans and pathogenic microbes. Covers major groups of medically important microorganisms, pathological consequences of infection, diagnostic procedures, and clinical case problem-solving. Prerequisites: BIO 208; BIO 392 or HSC 215; or graduate standing.
BIO 585
Conservation Medicine
3
Examines various diseases and their importance to wildlife, domestic animals, and humans. Epidemiology and ecology of diseases are discussed within the framework of conservation medicine. Prerequisites: BIO 208, 340; or graduate standing .
BIO 590
Cardiovascular Physiology
3
Basic principles of normal mammalian cardiovascular physiology. Prerequisites: BIO 392 or graduate standing.
BIO 591
Neurophysiology
3
Principles of nervous system function: cytology, electrophysiology, ion channels, membrane potentials, neurochemistry, synaptic function and its modification, sensory physiology. Prerequisites: BIO 392.
BIO 597
Special Topics In Biology
1-9
Topics of special interest that are not normally included in existing courses. Specific topics and instructor's prerequisites will be announced in Course Search and Registration. Prerequisite: See Course Search and Registration.
CHM 331
Inorganic Chemistry
3
Descriptive chemistry of selected main group and transition elements, coordination complexes, structures and properties of solids. Synthesis and characterization of inorganic compounds. Prerequisites: CHM 132 or CHM 161.
CHM 333
Bioinorganic Chemistry
3
Introduction to the function of metals and inorganic ions in living systems. Metal ion transport, storage, biomineralization, and processes of metalloproteins are examined. Prerequisite: CHM 132 or 161. Recommended: CHM 346.
CHM 511
Advanced Analytical Chemistry
4
Spectroscopic, electrochemical, and other techniques as applied to analytical chemistry. Prerequisites: CHM 211. Recommended: CHM 352 or 355.
CHM 513
Chemistry of Natural Waters
3
Fundamentals of laboratory and field analysis of water and their application to environmental studies. Prerequisites: CHM 211.
CHM 531
Advanced Inorganic Chemistry
3
Molecular structure and symmetry, acid-base and oxidation-reduction chemistry, reactivity of inorganic compounds from a thermodynamical basis, catalysis, solid state and organometallic compounds. Prerequisites: CHM 331. Recommended: CHM 352.
CHM 541
Intermediate Organic Chemistry
3
Mechanisms of organic reactions, emphasizing methods by which these are determined, including kinetics, principles of bonding, stereochemistry, and nuclear magnetic resonance in depth. Prerequisites: CHM 346. Recommended: CHM 351 or 355.
CHM 547
Advanced Chemistry Laboratory
2
Advanced synthesis, separation, and structure determination of organic and inorganic compounds. Prerequisite: CHM 349, 331.
CHM 551
Materials Chemistry: Inorganics and Nanomaterials
3
This course will provide a detailed survey of metals, semiconductors, ceramics, and nanomaterials, with a special emphasis on structure-property relationships. Students cannot receive credit for both SAM 700 and CHM 551. Prerequisites: CHM 331 or graduate status. Recommended: CHM 346.
CHM 555
Advanced Physical Chemistry
3
Advanced development and application of physical theories using a statistical mechanic approach to understanding of molecular energetics and kinetics. Prerequisites: CHM 352 or 355; MTH 233.
CHM 561
Polymer Chemistry
3
An introductory course on polymer synthesis, polymer theory, and basic characterization techniques. Prerequisites: CHM 346, 352.
CHM 562
Industrial Chemistry
3
Treatment of the following three primary areas: 1) actual chemistry of industry, 2) the technology of industry, and 3) the industrial chemical environment. Prerequisite: CHM 346.
CHM 564
Polymer Technology
3
A consideration of the major groups of technologically important polymers, including raw material base, the important methods of manufacture, properties, processing, compounding, uses and testing. Prerequisite: CHM 561.
CHM 566
Introduction to Biomaterials
3
Introduction to biomaterials science, including materials properties, interactions between materials and living tissues, and materials and biological testing. Prerequisite: CHM 346 or graduate standing. Recommended: CHM 352 or 355, CHM 425 or 521, CHM 561, BIO 110.
CHM 567
Polymer Science Laboratory
2
Treatment of laboratory techniques common to polymer science: synthesis of polymers and the characterization of these materials by spectroscopic, thermal, and mechanical methods. Prerequisites: CHM 349. Corequisite: CHM 561.
CHM 568
Pharmaceutical Chemistry
3
Interdisciplinary introduction to the science of drug formulation, delivery and efficacy. Prerequisites: CHM 346 or 342 or graduate standing. Recommended: CHM 425 or 521, CHM 355, BIO 392.
CHM 571
Topics in Chemistry
1-9
Special topics in chemistry presented at an advanced undergraduate - beginning graduate level. Course may be taken for credit more than once; total credit not to exceed nine hours. Prerequisites: See Course Search and Registration.
CHM 583
Seminar in Chemistry
1-2
Presentation of technical material and training in the use of chemical literature. Prerequisites: 25 credit hours of chemistry courses or graduate standing.
